node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OME82429.1 | OME82433.1 | BK122_10695 | BK122_10715 | 2,3-diketo-5-methylthiopentyl-1-phosphate enolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | LL-diaminopimelate aminotransferase; Produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.576 |
OME82429.1 | OME82580.1 | BK122_10695 | BK122_11525 | 2,3-diketo-5-methylthiopentyl-1-phosphate enolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.571 |
OME82429.1 | OME84814.1 | BK122_10695 | BK122_06740 | 2,3-diketo-5-methylthiopentyl-1-phosphate enolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional homocysteine S-methyltransferase/methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.832 |
OME82429.1 | mtnA | BK122_10695 | BK122_15945 | 2,3-diketo-5-methylthiopentyl-1-phosphate enolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | S-methyl-5-thioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.686 |
OME82429.1 | mtnB | BK122_10695 | BK122_10685 | 2,3-diketo-5-methylthiopentyl-1-phosphate enolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.999 |
OME82429.1 | mtnD | BK122_10695 | BK122_11520 | 2,3-diketo-5-methylthiopentyl-1-phosphate enolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acireductone dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.944 |
OME82429.1 | mtnK | BK122_10695 | BK122_15940 | 2,3-diketo-5-methylthiopentyl-1-phosphate enolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | S-methyl-5-thioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. | 0.805 |
OME82429.1 | mtnX | BK122_10695 | BK122_10690 | 2,3-diketo-5-methylthiopentyl-1-phosphate enolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate phosphatase; Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene). | 0.997 |
OME82433.1 | OME82429.1 | BK122_10715 | BK122_10695 | LL-diaminopimelate aminotransferase; Produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2,3-diketo-5-methylthiopentyl-1-phosphate enolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.576 |
OME82433.1 | OME82580.1 | BK122_10715 | BK122_11525 | LL-diaminopimelate aminotransferase; Produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.812 |
OME82433.1 | OME84814.1 | BK122_10715 | BK122_06740 | LL-diaminopimelate aminotransferase; Produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional homocysteine S-methyltransferase/methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.877 |
OME82433.1 | mtnB | BK122_10715 | BK122_10685 | LL-diaminopimelate aminotransferase; Produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.499 |
OME82433.1 | mtnD | BK122_10715 | BK122_11520 | LL-diaminopimelate aminotransferase; Produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acireductone dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.851 |
OME82580.1 | OME82429.1 | BK122_11525 | BK122_10695 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 2,3-diketo-5-methylthiopentyl-1-phosphate enolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.571 |
OME82580.1 | OME82433.1 | BK122_11525 | BK122_10715 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | LL-diaminopimelate aminotransferase; Produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.812 |
OME82580.1 | OME84504.1 | BK122_11525 | BK122_04975 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | LL-diaminopimelate aminotransferase; Produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.812 |
OME82580.1 | OME84704.1 | BK122_11525 | BK122_06110 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.812 |
OME82580.1 | OME84814.1 | BK122_11525 | BK122_06740 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Bifunctional homocysteine S-methyltransferase/methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
OME82580.1 | mtnA | BK122_11525 | BK122_15945 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | S-methyl-5-thioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.849 |
OME82580.1 | mtnB | BK122_11525 | BK122_10685 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.668 |