Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dapA_1Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (289 aa)    
Predicted Functional Partners:
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 
 0.993
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
 
 
 0.993
dapG
Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; diaminopimelate sensitive; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family.
 
  
 0.992
hom
Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.938
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
 0.927
AMM92724.1
Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.920
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
  
 
0.910
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
 
  
 0.845
AMM92507.1
Dipicolinate synthase subunit A; Catalyzes the synthesis of dipicolinic acid from dihydroxydipicolinic acid; plays a role in spore heat resistance; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.814
spoVFB
Dipicolinate synthase subunit B; Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA).
    
 0.804
Your Current Organism:
Bacillus simplex
NCBI taxonomy Id: 1478
Other names: ATCC 49097, Arthrobacter sp. CHR2P1B2-M, B. simplex, Bacillus maroccanus, Bacillus sp. JP44SK12, Bacillus sp. JP44SK13, Bacillus sp. JP44SK25, Bacillus sp. JP44SK26, Bacillus sp. JP44SK29, Bacillus sp. JP44SK30, Bacillus sp. JP44SK31, Bacillus sp. JP44SK32, CCUG 28889, CIP 106934, IFO 15720, JCM 12307, LMG 11160, LMG:11160, NBRC 15720, NRRL NRS-960
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