STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
accCBiotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (454 aa)    
Predicted Functional Partners:
aas
Bifunctional protein aas; Product derived from UniProtKB/Trembl:F8L0C5;Gene name derived from UniProtKB/Trembl:F8L0C5;EC number derived from UniProtKB/Trembl:F8L0C5.
  
 
 0.999
accB
Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 0.999
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
 0.999
accA
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
 
 0.998
fabD
Malonyl CoA-acyl carrier protein transacylase; Product derived from UniProtKB/Swiss-Prot:P71019;Gene name derived from UniProtKB/Swiss-Prot:P71019;EC number derived from UniProtKB/Swiss-Prot:P71019.
 
 
 0.996
fabH
3-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
  
 
 0.993
bkdB
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex; Product derived from UniProtKB/Swiss-Prot:P09062;Gene name derived from UniProtKB/Swiss-Prot:P09062;EC number derived from UniProtKB/Swiss-Prot:P09062.
  
 0.967
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.944
birA
Bifunctional protein BirA; Product derived from UniProtKB/Swiss-Prot:P0CI75;Gene name derived from UniProtKB/Swiss-Prot:P0CI75;EC number derived from UniProtKB/Swiss-Prot:P0CI75.
 
  
 0.932
pyk
Pyruvate kinase; Product derived from UniProtKB/Swiss-Prot:Q02499;Gene name derived from UniProtKB/Swiss-Prot:Q02499;EC number derived from UniProtKB/Swiss-Prot:Q02499; Belongs to the pyruvate kinase family.
   
 
 0.904
Your Current Organism:
Neochlamydia sp. EPS4
NCBI taxonomy Id: 1478175
Other names: N. sp. EPS4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.