STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKP46254.1Acetaldehyde dehydrogenaseacetylating; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (294 aa)    
Predicted Functional Partners:
AKP46255.1
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 0.998
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 0.983
AKP46253.1
4-oxalocrotonate decarboxylase.
 
  
 0.977
AKP46256.1
4-oxalocrotonate decarboxylase.
 
  
 0.977
AKP46943.1
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.907
AKP45740.1
Acetyl-CoA acetyltransferase; 3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
     
 0.905
AKP47363.1
Acetyl-CoA acetyltransferase; 3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
     
 0.905
AKP47751.1
Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
     
 0.905
AKP48127.1
Acyl-coenzyme A synthetases/AMP-fattyacid ligases YtcI-like.
     
 0.905
AKP48141.1
Acetyl-coenzyme A synthetase.
     
 0.905
Your Current Organism:
Bacillus smithii
NCBI taxonomy Id: 1479
Other names: B. smithii, CCUG 27413, CIP 103790, DSM 4216, IFO 15311, JCM 9076, LMG 12526, LMG:12526, NBRC 15311, NRRL NRS-173
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