node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKP45436.1 | mecA | BSM4216_0037 | BSM4216_1113 | DNA replication initiation control protein YabA; Involved in initiation control of chromosome replication. Belongs to the YabA family. | Negative regulator of genetic competence MecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC. | 0.651 |
AKP45491.1 | mecA | BSM4216_0108 | BSM4216_1113 | ATP-binding subunit ClpC Negative regulator of genetic competence clcC/mecB; Belongs to the ClpA/ClpB family. | Negative regulator of genetic competence MecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC. | 0.824 |
AKP46331.1 | AKP46421.1 | BSM4216_1030 | BSM4216_1121 | Competence transcription factor. | YjbH-likeGTP pyrophosphokinase domain. | 0.672 |
AKP46331.1 | AKP48157.1 | BSM4216_1030 | BSM4216_2925 | Competence transcription factor. | Hypothetical protein; Belongs to the UPF0354 family. | 0.760 |
AKP46331.1 | AKP48211.1 | BSM4216_1030 | BSM4216_2979 | Competence transcription factor. | 8-oxo-dGTPase Bsu YtkD 8-oxo-GTPase Bsu YtkD; Belongs to the Nudix hydrolase family. | 0.680 |
AKP46331.1 | ezrA | BSM4216_1030 | BSM4216_2899 | Competence transcription factor. | Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | 0.579 |
AKP46331.1 | mecA | BSM4216_1030 | BSM4216_1113 | Competence transcription factor. | Negative regulator of genetic competence MecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC. | 0.684 |
AKP46414.1 | AKP48157.1 | BSM4216_1114 | BSM4216_2925 | Competence protein CoiA. | Hypothetical protein; Belongs to the UPF0354 family. | 0.404 |
AKP46414.1 | ezrA | BSM4216_1114 | BSM4216_2899 | Competence protein CoiA. | Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | 0.755 |
AKP46414.1 | mecA | BSM4216_1114 | BSM4216_1113 | Competence protein CoiA. | Negative regulator of genetic competence MecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC. | 0.720 |
AKP46421.1 | AKP46331.1 | BSM4216_1121 | BSM4216_1030 | YjbH-likeGTP pyrophosphokinase domain. | Competence transcription factor. | 0.672 |
AKP46421.1 | AKP48157.1 | BSM4216_1121 | BSM4216_2925 | YjbH-likeGTP pyrophosphokinase domain. | Hypothetical protein; Belongs to the UPF0354 family. | 0.727 |
AKP46421.1 | AKP48211.1 | BSM4216_1121 | BSM4216_2979 | YjbH-likeGTP pyrophosphokinase domain. | 8-oxo-dGTPase Bsu YtkD 8-oxo-GTPase Bsu YtkD; Belongs to the Nudix hydrolase family. | 0.725 |
AKP46421.1 | ezrA | BSM4216_1121 | BSM4216_2899 | YjbH-likeGTP pyrophosphokinase domain. | Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | 0.644 |
AKP46421.1 | mecA | BSM4216_1121 | BSM4216_1113 | YjbH-likeGTP pyrophosphokinase domain. | Negative regulator of genetic competence MecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC. | 0.686 |
AKP46643.1 | mecA | BSM4216_1362 | BSM4216_1113 | ClpB protein; Belongs to the ClpA/ClpB family. | Negative regulator of genetic competence MecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC. | 0.758 |
AKP48157.1 | AKP46331.1 | BSM4216_2925 | BSM4216_1030 | Hypothetical protein; Belongs to the UPF0354 family. | Competence transcription factor. | 0.760 |
AKP48157.1 | AKP46414.1 | BSM4216_2925 | BSM4216_1114 | Hypothetical protein; Belongs to the UPF0354 family. | Competence protein CoiA. | 0.404 |
AKP48157.1 | AKP46421.1 | BSM4216_2925 | BSM4216_1121 | Hypothetical protein; Belongs to the UPF0354 family. | YjbH-likeGTP pyrophosphokinase domain. | 0.727 |
AKP48157.1 | AKP48211.1 | BSM4216_2925 | BSM4216_2979 | Hypothetical protein; Belongs to the UPF0354 family. | 8-oxo-dGTPase Bsu YtkD 8-oxo-GTPase Bsu YtkD; Belongs to the Nudix hydrolase family. | 0.775 |