STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKP46699.1Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex. (469 aa)    
Predicted Functional Partners:
AKP46698.1
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 0.999
AKP46697.1
Pyruvate dehydrogenase E1 component beta subunit.
 
 0.997
AKP45631.1
Dihydrolipoamide acetyltransferase component.
 0.995
AKP47726.1
Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex.
 0.995
AKP45948.1
Dihydrolipoamide acetyltransferase component.
 0.994
pdhA
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 
 0.994
AKP47344.1
Dihydrolipoamide succinyltransferase component E2of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.994
odhA
2-oxoglutarate dehydrogenase E1 component; E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
  
 0.986
AKP47727.1
Branched-chain alpha-keto acid dehydrogenaseE1 componentbeta subunit.
 
 0.983
gcvH
Glycine cleavage system H protein; Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate; Belongs to the GcvH family.
 
  
 0.979
Your Current Organism:
Bacillus smithii
NCBI taxonomy Id: 1479
Other names: B. smithii, CCUG 27413, CIP 103790, DSM 4216, IFO 15311, JCM 9076, LMG 12526, LMG:12526, NBRC 15311, NRRL NRS-173
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.