node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKP46087.1 | AKP46269.1 | BSM4216_0751 | BSM4216_0963 | 5,10-methylenetetrahydrofolate reductase; Homocysteine S-methyltransferase. | Acetolactate synthase large subunit. | 0.474 |
AKP46087.1 | AKP47360.1 | BSM4216_0751 | BSM4216_2110 | 5,10-methylenetetrahydrofolate reductase; Homocysteine S-methyltransferase. | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.510 |
AKP46087.1 | AKP47361.1 | BSM4216_0751 | BSM4216_2111 | 5,10-methylenetetrahydrofolate reductase; Homocysteine S-methyltransferase. | Homoserine dehydrogenase. | 0.960 |
AKP46087.1 | asd | BSM4216_0751 | BSM4216_2064 | 5,10-methylenetetrahydrofolate reductase; Homocysteine S-methyltransferase. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.472 |
AKP46087.1 | ilvC | BSM4216_0751 | BSM4216_0965 | 5,10-methylenetetrahydrofolate reductase; Homocysteine S-methyltransferase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.468 |
AKP46087.1 | metAA | BSM4216_0751 | BSM4216_0731 | 5,10-methylenetetrahydrofolate reductase; Homocysteine S-methyltransferase. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.974 |
AKP46087.1 | thrB | BSM4216_0751 | BSM4216_2109 | 5,10-methylenetetrahydrofolate reductase; Homocysteine S-methyltransferase. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.888 |
AKP46269.1 | AKP46087.1 | BSM4216_0963 | BSM4216_0751 | Acetolactate synthase large subunit. | 5,10-methylenetetrahydrofolate reductase; Homocysteine S-methyltransferase. | 0.474 |
AKP46269.1 | AKP47360.1 | BSM4216_0963 | BSM4216_2110 | Acetolactate synthase large subunit. | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.461 |
AKP46269.1 | AKP47361.1 | BSM4216_0963 | BSM4216_2111 | Acetolactate synthase large subunit. | Homoserine dehydrogenase. | 0.993 |
AKP46269.1 | AKP48503.1 | BSM4216_0963 | BSM4216_3317 | Acetolactate synthase large subunit. | D-malic enzyme; Tartrate dehydrogenase. | 0.969 |
AKP46269.1 | ilvC | BSM4216_0963 | BSM4216_0965 | Acetolactate synthase large subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.998 |
AKP46269.1 | leuB | BSM4216_0963 | BSM4216_0967 | Acetolactate synthase large subunit. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.994 |
AKP46269.1 | leuD | BSM4216_0963 | BSM4216_0969 | Acetolactate synthase large subunit. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.922 |
AKP46269.1 | thrB | BSM4216_0963 | BSM4216_2109 | Acetolactate synthase large subunit. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.468 |
AKP47360.1 | AKP46087.1 | BSM4216_2110 | BSM4216_0751 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 5,10-methylenetetrahydrofolate reductase; Homocysteine S-methyltransferase. | 0.510 |
AKP47360.1 | AKP46269.1 | BSM4216_2110 | BSM4216_0963 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Acetolactate synthase large subunit. | 0.461 |
AKP47360.1 | AKP47361.1 | BSM4216_2110 | BSM4216_2111 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Homoserine dehydrogenase. | 0.997 |
AKP47360.1 | AKP48503.1 | BSM4216_2110 | BSM4216_3317 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | D-malic enzyme; Tartrate dehydrogenase. | 0.404 |
AKP47360.1 | asd | BSM4216_2110 | BSM4216_2064 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.616 |