STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. (156 aa)    
Predicted Functional Partners:
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
 
 
 0.999
ribB-2
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
 
 
 0.999
GAM72983.1
Diaminohydroxyphosphoribosylaminopyrimidine deaminase.
 
 0.997
GAM72984.1
Diaminohydroxyphosphoribosylaminopyrimidine deaminase.
 
 0.997
GAM72985.1
Riboflavin synthase eubacterial/eukaryotic.
 
 0.994
GAM72986.1
Riboflavin synthase eubacterial/eukaryotic.
 
 0.994
GAM75694.1
Riboflavin synthase eubacterial/eukaryotic.
 
 0.990
GAM75460.1
GTP cyclohydrolase II.
 
 
 0.985
nusB
Transcription termination protein nusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
  
  
 0.970
GAM78653.1
Riboflavin kinase; Belongs to the ribF family.
  
 
 0.945
Your Current Organism:
Vibrio ishigakensis
NCBI taxonomy Id: 1481914
Other names: JCM 19231, LMG 28703, LMG:28703, V. ishigakensis, Vibrio ishigakensis Gao et al. 2018, Vibrio sp. C1(2016), Vibrio sp. C212, Vibrio sp. C216, Vibrio sp. C5(2016), Vibrio sp. C64, Vibrio sp. JCM 19231, Vibrio sp. JCM 19232, Vibrio sp. JCM 19241, strain c1
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