STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAM73175.12-oxoglutarate dehydrogenase E1 component. (73 aa)    
Predicted Functional Partners:
GAM73176.1
Dihydrolipoamide succinyltransferase component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.999
GAM72780.1
Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.997
GAM73174.1
2-oxoglutarate dehydrogenase E1 component.
     0.993
GAM73173.1
2-oxoglutarate dehydrogenase E1 component.
     0.987
GAM73177.1
succinyl-CoA ligase (ADP-forming) beta chain.
  
 0.954
GAM73178.1
succinyl-CoA ligase (ADP-forming) beta chain.
  
 0.941
GAM73179.1
succinyl-CoA ligase (ADP-forming) alpha chain.
  
 0.937
GAM73180.1
succinyl-CoA ligase (ADP-forming) alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.937
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
   
 
 0.901
GAM76599.1
Ribose-phosphate pyrophosphokinase.
    
 0.897
Your Current Organism:
Vibrio ishigakensis
NCBI taxonomy Id: 1481914
Other names: JCM 19231, LMG 28703, LMG:28703, V. ishigakensis, Vibrio ishigakensis Gao et al. 2018, Vibrio sp. C1(2016), Vibrio sp. C212, Vibrio sp. C216, Vibrio sp. C5(2016), Vibrio sp. C64, Vibrio sp. JCM 19231, Vibrio sp. JCM 19232, Vibrio sp. JCM 19241, strain c1
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