STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAM76502.1Exodeoxyribonuclease III. (269 aa)    
Predicted Functional Partners:
nfo
Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
    
 0.989
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
 0.973
hfq
RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
    
 
 0.961
GAM78529.1
DNA polymerase III beta subunit.
   
 0.954
GAM78530.1
DNA polymerase III beta subunit.
   
 0.954
GAM77557.1
A/G-specific adenine glycosylase.
  
 
 0.949
GAM78098.1
Hypothetical protein.
  
 0.947
GAM78099.1
ADA regulatory protein.
  
 0.947
GAM77556.1
A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
    
 0.942
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.921
Your Current Organism:
Vibrio ishigakensis
NCBI taxonomy Id: 1481914
Other names: JCM 19231, LMG 28703, LMG:28703, V. ishigakensis, Vibrio ishigakensis Gao et al. 2018, Vibrio sp. C1(2016), Vibrio sp. C212, Vibrio sp. C216, Vibrio sp. C5(2016), Vibrio sp. C64, Vibrio sp. JCM 19231, Vibrio sp. JCM 19232, Vibrio sp. JCM 19241, strain c1
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