STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAM74121.12-amino-3-ketobutyrate coenzyme A ligase. (68 aa)    
Predicted Functional Partners:
GAM74120.1
2-amino-3-ketobutyrate coenzyme A ligase.
     0.994
tdh
L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.
 
 
 0.984
bioD
Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
  
 
 0.845
bioC
Biotin synthesis protein bioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
  
 
 0.810
GAM75793.1
Sensory box histidine kinase.
  
 
 0.765
GAM75795.1
Diguanylate cyclase.
  
 
 0.765
GAM75797.1
Sensory box histidine kinase.
  
 
 0.765
GAM75801.1
Sensory box histidine kinase.
  
 
 0.748
GAM75802.1
Adenylate cyclase.
  
 
 0.744
bioH
Biotin synthesis protein bioH; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
  
 0.742
Your Current Organism:
Vibrio ishigakensis
NCBI taxonomy Id: 1481914
Other names: JCM 19231, LMG 28703, LMG:28703, V. ishigakensis, Vibrio ishigakensis Gao et al. 2018, Vibrio sp. C1(2016), Vibrio sp. C212, Vibrio sp. C216, Vibrio sp. C5(2016), Vibrio sp. C64, Vibrio sp. JCM 19231, Vibrio sp. JCM 19232, Vibrio sp. JCM 19241, strain c1
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