STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
GAM77007.1Cell division protein ftsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (224 aa)    
Predicted Functional Partners:
ftsA
Cell division protein ftsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
 
 0.997
GAM77006.1
Cell division protein ftsA.
 
 
 0.996
GAM77008.1
Cell division protein ftsZ.
     0.994
zipA
Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
  
 
 0.973
GAM76684.1
Superfamily II DNA and RNA helicase; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
    
 
 0.955
zapD
Hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
    
 
 0.942
GAM75619.1
Hypothetical protein.
    
 
 0.922
GAM75620.1
Hypothetical protein.
    
 
 0.922
slmA
Transcriptional regulator slmA; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
    
 
 0.909
GAM77001.1
Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II).
 
 
 0.837
Your Current Organism:
Vibrio ishigakensis
NCBI taxonomy Id: 1481914
Other names: JCM 19231, LMG 28703, LMG:28703, V. ishigakensis, Vibrio ishigakensis Gao et al. 2018, Vibrio sp. C1(2016), Vibrio sp. C212, Vibrio sp. C216, Vibrio sp. C5(2016), Vibrio sp. C64, Vibrio sp. JCM 19231, Vibrio sp. JCM 19232, Vibrio sp. JCM 19241, strain c1
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