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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APC47395.1Multidrug ABC transporter permease/ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (581 aa)    
Predicted Functional Partners:
APC47396.1
Multidrug ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 
0.983
APC50173.1
Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.793
APC48112.1
Polar amino acid ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 
0.670
APC49298.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.668
APC48688.1
Calcium-translocating P-type ATPase, SERCA-type; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.645
APC48906.1
Thioredoxin family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.610
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.609
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 0.593
parE
DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily.
    
 0.593
APC48665.1
[acyl-carrier-protein] S-malonyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.590
Your Current Organism:
Virgibacillus halodenitrificans
NCBI taxonomy Id: 1482
Other names: ATCC 49067, Bacillus halodenitrificans, DSM 10037, JCM 12304, LMG 9818, LMG:9818, NBRC 102361, V. halodenitrificans
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