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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
addAHelicase-exonuclease AddAB subunit AddA; ATP-dependent DNA helicase. (1241 aa)    
Predicted Functional Partners:
addB
Helicase-exonuclease AddAB subunit AddB; ATP-dependent DNA helicase; Belongs to the helicase family. AddB/RexB type 1 subfamily.
 
 0.999
recD2
Hypothetical protein; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.
  
 0.916
APC50077.1
Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.916
APC47178.1
ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.804
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
    
 0.744
APC48238.1
SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.699
sbcD
Exonuclease sbcCD subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
  
 0.595
dinG
ATP-dependent helicase DinG; 3'-5' exonuclease.
 
  
 0.576
APC47466.1
Signal peptidase I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.
  
    0.501
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.498
Your Current Organism:
Virgibacillus halodenitrificans
NCBI taxonomy Id: 1482
Other names: ATCC 49067, Bacillus halodenitrificans, DSM 10037, JCM 12304, LMG 9818, LMG:9818, NBRC 102361, V. halodenitrificans
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