STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
minCHypothetical protein; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (218 aa)    
Predicted Functional Partners:
OAR03708.1
Septum site-determining protein MinD; ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
OAR03704.1
Hypothetical protein; Involved in formation and maintenance of cell shape.
  
  
 0.959
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
   
 
 0.945
OAR03703.1
Rod shape-determining protein MreB; Functions in MreBCD complex in some organisms; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.872
sepF
Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
  
  
 0.781
OAR03870.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.741
ffh
Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
   
  
 0.721
ftsA
Hypothetical protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
   
  
 0.654
mltG
Hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
 
  
 0.607
OAR04716.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.600
Your Current Organism:
Hydrogenibacillus schlegelii
NCBI taxonomy Id: 1484
Other names: ATCC 43741, Bacillus schlegelii, CCUG 26017, CIP 106933, DSM 2000, H. schlegelii, LMG 7133, LMG:7133, strain MA 48
Server load: medium (62%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.