Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
birAHypothetical protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. (317 aa)    
Predicted Functional Partners:
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 
 0.942
OAR03740.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
 
  
 0.933
tadA
Adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
  
    0.918
OAR05371.1
propionyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.917
OAR04980.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.913
coaX
Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
 
    0.897
OAR03713.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
 
 
 0.890
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
 
 0.857
dapB
Hypothetical protein; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
  
  
 0.846
OAR05374.1
Biotin carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.835
Your Current Organism:
Hydrogenibacillus schlegelii
NCBI taxonomy Id: 1484
Other names: ATCC 43741, Bacillus schlegelii, CCUG 26017, CIP 106933, DSM 2000, H. schlegelii, LMG 7133, LMG:7133, strain MA 48
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