Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OAR03948.1Sigma-29; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the mother cell at the onset of sporulation; Derived by automated computational analysis using gene prediction method: Protein Homology. (237 aa)    
Predicted Functional Partners:
OAR03946.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.857
OAR03261.1
Hypothetical protein; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.817
OAR03874.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.801
OAR04108.1
Stage V sporulation protein T; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.800
OAR04196.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.800
OAR04224.1
Stage III sporulation protein D; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.799
OAR03890.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.795
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.782
OAR05534.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
    0.780
OAR03403.1
Stage V sporulation protein AD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.775
Your Current Organism:
Hydrogenibacillus schlegelii
NCBI taxonomy Id: 1484
Other names: ATCC 43741, Bacillus schlegelii, CCUG 26017, CIP 106933, DSM 2000, H. schlegelii, LMG 7133, LMG:7133, strain MA 48
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