Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
OAR03629.1Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (279 aa)    
Predicted Functional Partners:
SA87_09715
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 0.998
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 0.968
OAR05180.1
2-keto-4-pentenoate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.959
SA87_09940
FAA_hydrolase domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.952
OAR04040.1
2-oxopent-4-enoate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.951
OAR05375.1
3-hydroxy-3-methylglutaryl-CoA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.894
OAR04860.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.894
OAR04991.1
Pyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.886
OAR03799.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.819
OAR04012.1
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.800
Your Current Organism:
Hydrogenibacillus schlegelii
NCBI taxonomy Id: 1484
Other names: ATCC 43741, Bacillus schlegelii, CCUG 26017, CIP 106933, DSM 2000, H. schlegelii, LMG 7133, LMG:7133, strain MA 48
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