Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
OAR04978.1PemK family transcriptional regulator; Toxic component of a type II toxin-antitoxin (TA) system. (116 aa)    
Predicted Functional Partners:
OAR04977.1
Antitoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.992
OAR05501.1
NAD+ synthetase; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family.
  
 
 0.860
OAR04598.1
HxlR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.742
OAR04976.1
Hypothetical protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
       0.590
gyrB
DNA topoisomerase IV subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
      
 0.552
OAR04975.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.506
OAR04979.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.484
OAR03914.1
Cytochrome C biogenesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.467
acpS
Hypothetical protein; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
     
 0.446
OAR04538.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CtsR family.
  
     0.433
Your Current Organism:
Hydrogenibacillus schlegelii
NCBI taxonomy Id: 1484
Other names: ATCC 43741, Bacillus schlegelii, CCUG 26017, CIP 106933, DSM 2000, H. schlegelii, LMG 7133, LMG:7133, strain MA 48
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