STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OSB10154.1Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (376 aa)    
Predicted Functional Partners:
lepA
Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
 0.880
OSB09480.1
Coproporphyrinogen dehydrogenase HemZ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.824
OSB12585.1
methylcobamide--CoM methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the uroporphyrinogen decarboxylase family.
  
 
 0.813
OSB12570.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.775
OSB12587.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the uroporphyrinogen decarboxylase family.
  
 
 0.743
rlmN
23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
 
   
 0.705
hrcA
Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
  
    0.701
OSB07889.1
uroporphyrinogen-III C-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.682
OSB09332.1
methylcobamide--CoM methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the uroporphyrinogen decarboxylase family.
  
 
 0.676
OSB12582.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the uroporphyrinogen decarboxylase family.
  
 
 0.670
Your Current Organism:
Paraclostridium bifermentans
NCBI taxonomy Id: 1490
Other names: ATCC 638, BCRC 14542, Bacillus bifermentans, Bacillus bifermentans sporogenes, Bacillus centrosporogenes, CCRC 14542, CCRC:14542, CCUG 36626, CIP 104309, Clostridium bifermentans, DSM 14991, Martellillus bifermentans, NCIMB 10716, NCTC 13019, P. bifermentans
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