STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OSB09836.1MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)    
Predicted Functional Partners:
OSB10190.1
MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.703
OSB08920.1
MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.673
OSB09681.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.631
OSB12004.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.624
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 
 0.570
OSB08643.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.570
OSB09680.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.529
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.526
OSB10599.1
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.
  
 
 0.516
OSB10906.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.470
Your Current Organism:
Paraclostridium bifermentans
NCBI taxonomy Id: 1490
Other names: ATCC 638, BCRC 14542, Bacillus bifermentans, Bacillus bifermentans sporogenes, Bacillus centrosporogenes, CCRC 14542, CCRC:14542, CCUG 36626, CIP 104309, Clostridium bifermentans, DSM 14991, Martellillus bifermentans, NCIMB 10716, NCTC 13019, P. bifermentans
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