node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OSB07922.1 | OSB08149.1 | B2H97_16200 | B2H97_15175 | RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | PIN/TRAM domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.461 |
OSB08146.1 | OSB08149.1 | B2H97_15160 | B2H97_15175 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. | PIN/TRAM domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.403 |
OSB08146.1 | disA | B2H97_15160 | B2H97_15170 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. | DNA integrity scanning protein DisA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis. | 0.525 |
OSB08146.1 | radA | B2H97_15160 | B2H97_15165 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.618 |
OSB08149.1 | OSB07922.1 | B2H97_15175 | B2H97_16200 | PIN/TRAM domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.461 |
OSB08149.1 | OSB08146.1 | B2H97_15175 | B2H97_15160 | PIN/TRAM domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. | 0.403 |
OSB08149.1 | OSB08158.1 | B2H97_15175 | B2H97_15220 | PIN/TRAM domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.453 |
OSB08149.1 | OSB08159.1 | B2H97_15175 | B2H97_15225 | PIN/TRAM domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA polymerase factor sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. | 0.493 |
OSB08149.1 | disA | B2H97_15175 | B2H97_15170 | PIN/TRAM domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA integrity scanning protein DisA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis. | 0.814 |
OSB08149.1 | ispD | B2H97_15175 | B2H97_15180 | PIN/TRAM domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.831 |
OSB08149.1 | ispF | B2H97_15175 | B2H97_15185 | PIN/TRAM domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.651 |
OSB08149.1 | radA | B2H97_15175 | B2H97_15165 | PIN/TRAM domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.857 |
OSB08149.1 | tilS | B2H97_15175 | B2H97_12870 | PIN/TRAM domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA lysidine(34) synthetase TilS; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.409 |
OSB08158.1 | OSB08149.1 | B2H97_15220 | B2H97_15175 | Ribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | PIN/TRAM domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.453 |
OSB08158.1 | OSB08159.1 | B2H97_15220 | B2H97_15225 | Ribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA polymerase factor sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. | 0.842 |
OSB08159.1 | OSB08149.1 | B2H97_15225 | B2H97_15175 | RNA polymerase factor sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. | PIN/TRAM domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.493 |
OSB08159.1 | OSB08158.1 | B2H97_15225 | B2H97_15220 | RNA polymerase factor sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. | Ribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.842 |
disA | OSB08146.1 | B2H97_15170 | B2H97_15160 | DNA integrity scanning protein DisA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. | 0.525 |
disA | OSB08149.1 | B2H97_15170 | B2H97_15175 | DNA integrity scanning protein DisA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis. | PIN/TRAM domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.814 |
disA | ispD | B2H97_15170 | B2H97_15180 | DNA integrity scanning protein DisA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.665 |