STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (419 aa)    
Predicted Functional Partners:
A0A194X5S7
Ribonuclease H-like protein.
    
 0.980
A0A132BEN9
Uncharacterized protein.
   
 0.930
A0A194XH92
Putative Asparaginyl-tRNA synthetase, cytoplasmic.
   
 0.930
A0A194X436
RMI1_N domain-containing protein.
    
 0.869
A0A194XMH7
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.855
A0A194XTT2
DNA repair protein.
   
 0.846
A0A194X366
Uncharacterized protein.
     
 0.842
SLX4
Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
    
 0.835
A0A132B6S0
ERCC4 domain-containing protein.
   
 0.827
A0A194XKQ6
Uncharacterized protein.
   
 0.825
Your Current Organism:
Phialocephala scopiformis
NCBI taxonomy Id: 149040
Other names: CBS 468.94, P. scopiformis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.