STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALP89846.1Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)    
Predicted Functional Partners:
hisI
phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
  
  
 0.904
ALP89847.1
Exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.814
hisF
Imidazole glycerol phosphate synthase cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.653
ALP89845.1
Permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.632
hisH
Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
  
 0.597
hisA
1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.587
hisB
Imidazoleglycerol-phosphate dehydratase; Catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.584
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
  
 0.568
ALP91148.1
Aminotransferase class I/II; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.554
ALR90695.1
(p)ppGpp synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.534
Your Current Organism:
Clostridium butyricum
NCBI taxonomy Id: 1492
Other names: ATCC 19398, Amylobacter navicula, Bacillus amylobacter, Bacillus butyricus, Bacillus navicula, Bacterium navicula, C. butyricum, CCUG 4217, CIP 103309, Clostridium kainantoi, Clostridium naviculum, Clostridium pseudotetanicum, DSM 10702, HAMBI 482, IAM 14194, IFO 13949, Metallacter amylobacter, NBRC 13949, NCCB 89156, NCIB 7423, NCIMB 7423, NCTC 7423, VPI 3266
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