STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ALR90249.1DNA replication protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa)    
Predicted Functional Partners:
topB
DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...]
     
 0.931
ALR90250.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.861
ALP89791.1
DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.852
ALP91551.1
RNA polymerase subunit sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.786
ALR90246.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.741
ALR90247.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.741
ALR90248.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.741
dnaB
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
 
 0.658
dnaB-2
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
 
 0.658
dnaB-3
Replicative DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.658
Your Current Organism:
Clostridium butyricum
NCBI taxonomy Id: 1492
Other names: ATCC 19398, Amylobacter navicula, Bacillus amylobacter, Bacillus butyricus, Bacillus navicula, Bacterium navicula, C. butyricum, CCUG 4217, CIP 103309, Clostridium kainantoi, Clostridium naviculum, Clostridium pseudotetanicum, DSM 10702, HAMBI 482, IAM 14194, IFO 13949, Metallacter amylobacter, NBRC 13949, NCCB 89156, NCIB 7423, NCIMB 7423, NCTC 7423, VPI 3266
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