Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AQ1_022055-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (117 aa)    
Predicted Functional Partners:
AQ1_02203
2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase.
 
 0.997
cda1
Chitin deacetylase 1.
 
 
  0.960
AQ1_02209
Putative membrane protein.
 
  
 0.960
XDH
Xanthine dehydrogenase/oxidase.
 
     0.945
guaD
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
 
   
 0.938
hxA
Xanthine dehydrogenase.
 
     0.935
AQ1_02208
Xanthine dehydrogenase accessory protein XdhC.
 
     0.932
allA
Ureidoglycolate lyase.
 
    0.892
alc2
Putative allantoicase 2; Belongs to the allantoicase family.
 
 
  0.865
yedZ
Sulfoxide reductase heme-binding subunit YedZ; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalyti [...]
   
    0.792
Your Current Organism:
alpha proteobacterium Q1
NCBI taxonomy Id: 1492281
Other names: a. proteobacterium Q-1, alpha proteobacterium Q-1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.