Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D2HGDHD-2-hydroxyglutarate dehydrogenase, mitochondrial. (475 aa)    
Predicted Functional Partners:
etfA
Electron transfer flavoprotein subunit alpha.
 
 0.948
etfB
Electron transfer flavoprotein subunit beta.
 
 0.942
ccoP
Cbb3-type cytochrome c oxidase subunit CcoP; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
   
 0.937
adhB
Alcohol dehydrogenase cytochrome c subunit.
   
 0.901
gltB
Glutamate synthase [NADPH] large chain.
    
 0.843
maeB
NADP-dependent malic enzyme.
  
 
 0.832
tme
NADP-dependent malic enzyme.
  
 
 0.832
pdhB
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 0.817
ioxB
SCO1/SenC family protein; PMID:22447601.
   
 0.796
gyaR
Glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 
 0.791
Your Current Organism:
alpha proteobacterium Q1
NCBI taxonomy Id: 1492281
Other names: a. proteobacterium Q-1, alpha proteobacterium Q-1
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.