Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ygcBCRISPR-associated endonuclease/helicase Cas3. (858 aa)    
Predicted Functional Partners:
casC
CRISPR system Cascade subunit CasC.
 
 
 0.969
casD
CRISPR system Cascade subunit CasD.
 
 
 0.967
AQ1_02580
CRISPR type I-E/ECOLI-associated protein CasA/Cse1.
 
 
 0.963
ygbT
CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.871
AQ1_02584
CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI.
 
   
 0.842
ygbF
CRISPR-associated endoribonuclease Cas2.
 
     0.803
MJECL08
Putative protein.
 
     0.561
AQ1_02578
Hypothetical protein.
       0.493
Your Current Organism:
alpha proteobacterium Q1
NCBI taxonomy Id: 1492281
Other names: a. proteobacterium Q-1, alpha proteobacterium Q-1
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