Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gshbGlutathione synthetase; Belongs to the prokaryotic GSH synthase family. (312 aa)    
Predicted Functional Partners:
GSH1
Glutamate--cysteine ligase, chloroplastic; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
    
 0.906
GOR
Glutathione reductase, chloroplastic; Maintains high levels of reduced glutathione.
  
  
 0.829
pepA
Putative cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 
 0.820
ggt
Gamma-glutamyltranspeptidase.
    
 0.797
pepA-2
Putative cytosol aminopeptidase; Belongs to the peptidase M17 family.
   
 
 0.782
GstD4
Glutathione S-transferase D4.
    
 0.740
PRXIIE-1
peroxiredoxin-2E-1, chloroplastic; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
     
 0.723
gltB
Glutamate synthase [NADPH] large chain.
    
 0.716
yfcF
Glutathione S-transferase YfcF.
 
  
 0.691
grxC
Glutaredoxin-3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
 
  
 0.677
Your Current Organism:
alpha proteobacterium Q1
NCBI taxonomy Id: 1492281
Other names: a. proteobacterium Q-1, alpha proteobacterium Q-1
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