Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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tsaDtRNA N6-adenosine threonylcarbamoyltransferase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (368 aa)    
Predicted Functional Partners:
tsaB
tRNA threonylcarbamoyladenosine biosynthesis protein TsaB.
  
 0.987
tsaE
tRNA threonylcarbamoyladenosine biosynthesis protein TsaE.
  
 0.984
AQ1_02794
Hypothetical protein.
  
  
 0.757
ywlC
threonylcarbamoyl-AMP synthase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
  
 0.732
thrS
threonine--tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
  
 0.726
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
     
 0.714
holB
DNA polymerase III subunit delta'.
 
 
  0.701
AQ1_02793
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
  
 0.653
yciI
Protein YciI.
       0.652
gpsA
Glycerol-3-phosphate dehydrogenase; NAD(P)+; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
       0.652
Your Current Organism:
alpha proteobacterium Q1
NCBI taxonomy Id: 1492281
Other names: a. proteobacterium Q-1, alpha proteobacterium Q-1
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