node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANE49318.1 | ANE49319.1 | SY85_01180 | SY85_01185 | Thioredoxin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.696 |
ANE49318.1 | ANE49320.1 | SY85_01180 | SY85_01190 | Thioredoxin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.684 |
ANE49319.1 | ANE49318.1 | SY85_01185 | SY85_01180 | Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Thioredoxin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.696 |
ANE49319.1 | ANE49320.1 | SY85_01185 | SY85_01190 | Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.804 |
ANE49319.1 | ANE49355.1 | SY85_01185 | SY85_01395 | Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.991 |
ANE49319.1 | ANE49865.1 | SY85_01185 | SY85_04535 | Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | 0.583 |
ANE49319.1 | ANE50164.1 | SY85_01185 | SY85_06260 | Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.537 |
ANE49319.1 | ANE52769.1 | SY85_01185 | SY85_22115 | Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.994 |
ANE49319.1 | folE | SY85_01185 | SY85_00940 | Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.883 |
ANE49319.1 | folE-2 | SY85_01185 | SY85_08205 | Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.881 |
ANE49319.1 | ftsH | SY85_01185 | SY85_18865 | Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | ATPase AAA; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.522 |
ANE49319.1 | ribBA | SY85_01185 | SY85_22765 | Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.549 |
ANE49320.1 | ANE49318.1 | SY85_01190 | SY85_01180 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thioredoxin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.684 |
ANE49320.1 | ANE49319.1 | SY85_01190 | SY85_01185 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.804 |
ANE49355.1 | ANE49319.1 | SY85_01395 | SY85_01185 | Dihydropteroate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.991 |
ANE49355.1 | ANE49865.1 | SY85_01395 | SY85_04535 | Dihydropteroate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | 0.997 |
ANE49355.1 | ANE50164.1 | SY85_01395 | SY85_06260 | Dihydropteroate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.551 |
ANE49355.1 | ANE52769.1 | SY85_01395 | SY85_22115 | Dihydropteroate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
ANE49355.1 | folE | SY85_01395 | SY85_00940 | Dihydropteroate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.919 |
ANE49355.1 | folE-2 | SY85_01395 | SY85_08205 | Dihydropteroate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.933 |