node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANE49865.1 | ANE51629.1 | SY85_04535 | SY85_15075 | Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.536 |
ANE49865.1 | gcvP | SY85_04535 | SY85_06905 | Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.487 |
ANE49865.1 | thyA | SY85_04535 | SY85_06040 | Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.843 |
ANE50652.1 | ANE51629.1 | SY85_09195 | SY85_15075 | Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.403 |
ANE51628.1 | ANE51629.1 | SY85_15070 | SY85_15075 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.509 |
ANE51629.1 | ANE49865.1 | SY85_15075 | SY85_04535 | Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | 0.536 |
ANE51629.1 | ANE50652.1 | SY85_15075 | SY85_09195 | Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.403 |
ANE51629.1 | ANE51628.1 | SY85_15075 | SY85_15070 | Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.509 |
ANE51629.1 | ANE51630.1 | SY85_15075 | SY85_15080 | Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.463 |
ANE51629.1 | gcvP | SY85_15075 | SY85_06905 | Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.576 |
ANE51629.1 | thyA | SY85_15075 | SY85_06040 | Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.795 |
ANE51630.1 | ANE51629.1 | SY85_15080 | SY85_15075 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.463 |
gcvP | ANE49865.1 | SY85_06905 | SY85_04535 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | 0.487 |
gcvP | ANE51629.1 | SY85_06905 | SY85_15075 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.576 |
gcvP | thyA | SY85_06905 | SY85_06040 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.712 |
thyA | ANE49865.1 | SY85_06040 | SY85_04535 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | 0.843 |
thyA | ANE51629.1 | SY85_06040 | SY85_15075 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.795 |
thyA | gcvP | SY85_06040 | SY85_06905 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.712 |