ANE51682.1 protein (Flavisolibacter tropicus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ANE51682.1

DoxX-like family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (126 aa)

Predicted Functional Partners:

ANE51683.1

0.950

ANE51684.1

0.866

ANE52364.1

0.542

ANE51721.1

0.490

ANE49466.1

0.428

ANE53522.1

0.407

Your Current Organism:

Flavisolibacter tropicus

NCBI taxonomy Id: 1492898
Other names: F. tropicus, Flavisolibacter sp. LCS9, Flavisolibacter tropicus Lee et al. 2016, JCM 19972, KCTC 42070, strain LCS9

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANE49466.1	ANE51682.1	SY85_02085	SY85_15420	AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	DoxX-like family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.428
ANE51682.1	ANE49466.1	SY85_15420	SY85_02085	DoxX-like family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.428
ANE51682.1	ANE51683.1	SY85_15420	SY85_15425	DoxX-like family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.950
ANE51682.1	ANE51684.1	SY85_15420	SY85_15430	DoxX-like family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ArsR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.866
ANE51682.1	ANE51721.1	SY85_15420	SY85_15670	DoxX-like family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cell division protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.490
ANE51682.1	ANE52364.1	SY85_15420	SY85_19630	DoxX-like family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.542
ANE51682.1	ANE53522.1	SY85_15420	SY85_15415	DoxX-like family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.407
ANE51683.1	ANE51682.1	SY85_15425	SY85_15420	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	DoxX-like family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.950
ANE51683.1	ANE51684.1	SY85_15425	SY85_15430	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ArsR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.939
ANE51683.1	ANE51721.1	SY85_15425	SY85_15670	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cell division protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.546
ANE51683.1	ANE53522.1	SY85_15425	SY85_15415	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.407
ANE51684.1	ANE51682.1	SY85_15430	SY85_15420	ArsR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	DoxX-like family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.866
ANE51684.1	ANE51683.1	SY85_15430	SY85_15425	ArsR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.939
ANE51684.1	ANE53522.1	SY85_15430	SY85_15415	ArsR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.407
ANE51721.1	ANE51682.1	SY85_15670	SY85_15420	Cell division protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	DoxX-like family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.490
ANE51721.1	ANE51683.1	SY85_15670	SY85_15425	Cell division protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.546
ANE52364.1	ANE51682.1	SY85_19630	SY85_15420	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	DoxX-like family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.542
ANE53522.1	ANE51682.1	SY85_15415	SY85_15420	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	DoxX-like family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.407
ANE53522.1	ANE51683.1	SY85_15415	SY85_15425	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.407
ANE53522.1	ANE51684.1	SY85_15415	SY85_15430	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ArsR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.407

Network Stats

number of nodes:

11

number of edges:

27

average node degree:

4.91

avg. local clustering coefficient:

0.841

expected number of edges:

16

PPI enrichment p-value:

0.0103

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006289

Nucleotide-excision repair

4 of 40

2.09

2.13

5.60e-05

GO:0006310

DNA recombination

5 of 99

1.8

2.0

3.81e-05

GO:0006312

Mitotic recombination

3 of 13

2.46

1.98

0.00020

GO:0006302

Double-strand break repair

4 of 81

1.79

1.64

0.00033

GO:0000736

Double-strand break repair via single-strand annealing, removal of nonhomologous ends

2 of 2

3.09

1.64

0.0011

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003684

Damaged DNA binding

4 of 33

2.18

2.35

2.37e-05

GO:0003712

Transcription coregulator activity

4 of 73

1.83

1.72

0.00024

GO:0003697

Single-stranded DNA binding

3 of 40

1.97

1.33

0.0025

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016592

Mediator complex

4 of 18

2.44

3.2

6.98e-07

GO:0030894

Replisome

3 of 12

2.49

2.41

2.97e-05

GO:0005662

DNA replication factor A complex

2 of 2

3.09

1.83

0.00050

GO:0000110

Nucleotide-excision repair factor 1 complex

2 of 3

2.92

1.77

0.00062

GO:0140513

Nuclear protein-containing complex

9 of 638

1.24

1.72

4.83e-08

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:12559

Activator

4 of 7

2.85

3.69

1.52e-07

CL:9555

Mixed, incl. HDR through Single Strand Annealing (SSA), and Lagging Strand Synthesis

4 of 48

2.01

2.35

1.36e-05

CL:9639

Restriction endonuclease type II-like, and Putative DNA-binding domain superfamily

2 of 6

2.62

1.57

0.0013

CL:9576

DNA replication factor A complex, and DNA recombinase assembly

2 of 6

2.62

1.57

0.0013

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03420

Nucleotide excision repair

5 of 63

1.99

3.07

1.82e-07

map03430

Mismatch repair

3 of 50

1.87

1.55

0.00068

map03440

Homologous recombination

3 of 57

1.82

1.53

0.00068

map03030

DNA replication

3 of 66

1.75

1.47

0.00076

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-5696400

Dual Incision in GG-NER

4 of 30

2.22

2.72

3.95e-06

MAP-6781827

Transcription-Coupled Nucleotide Excision Repair (TC-NER)

5 of 82

1.88

2.44

3.95e-06

MAP-5696399

Global Genome Nucleotide Excision Repair (GG-NER)

4 of 44

2.05

2.43

1.03e-05

MAP-5696398

Nucleotide Excision Repair

5 of 92

1.83

2.39

3.95e-06

MAP-5696395

Formation of Incision Complex in GG-NER

3 of 15

2.4

2.27

4.97e-05

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005662

DNA replication factor A complex

3 of 3

3.09

2.97

3.93e-06

GOCC:0000110

Nucleotide-excision repair factor 1 complex

2 of 3

2.92

1.8

0.00054

GOCC:0000228

Nuclear chromosome

4 of 182

1.44

1.26

0.00079

GOCC:0005634

Nucleus

11 of 1500

0.96

1.13

2.96e-08

GOCC:0032991

Protein-containing complex

10 of 2556

0.69

0.61

7.65e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0010

Activator

4 of 18

2.44

3.32

4.05e-07

KW-0539

Nucleus

6 of 404

1.27

1.39

3.51e-05

KW-0805

Transcription regulation

4 of 176

1.45

1.28

0.00073

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01336

OB-fold nucleic acid binding domain

2 of 5

2.7

1.03

0.0136

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR011335

Restriction endonuclease type II-like

2 of 3

2.92

0.97

0.0178

IPR010994

RuvA domain 2-like

2 of 4

2.79

0.97

0.0178

IPR004365

OB-fold nucleic acid binding domain, AA-tRNA synthetase-type

2 of 5

2.7

0.97

0.0178

IPR012340

Nucleic acid-binding, OB-fold

3 of 63

1.77

0.89

0.0178

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (20%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About