STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrBAspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (307 aa)    
Predicted Functional Partners:
pyrI
Aspartate carbamoyltransferase regulatory subunit.
 
 0.999
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 0.999
pyrD
Dihydroorotate oxidase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
 
 
 0.996
pyrF
Orotidine-5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
 
  
 0.995
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.990
pyrR
Pyrimidine operon attenuation protein / uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
 
 
 0.990
SDL16776.1
Dihydropyrimidinase.
 
 0.990
pyrK_1
Dihydroorotate oxidase B, electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
 
 
 0.981
uraA
Uracil permease.
 
  
 0.960
SDL31170.1
Carbamate kinase; Belongs to the carbamate kinase family.
 
  
 0.891
Your Current Organism:
Clostridium cochlearium
NCBI taxonomy Id: 1494
Other names: ATCC 17787, BCRC 14471, Bacillus cochlearius, C. cochlearium, CCRC 14471, CCRC:14471, CCUG 31665, CIP 104319, Clostridium cochlearum, Clostridium lentoputrescens, NCCB 73036, NCIMB 10633, NCTC 13027
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