STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDK99958.1DNA processing protein. (364 aa)    
Predicted Functional Partners:
SDK99946.1
Magnesium chelatase family protein.
 
 0.954
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.890
SDL18572.1
Competence protein ComFC.
 
 
 0.852
SDK99923.1
Putative endonuclease; Belongs to the UPF0102 family.
 
    0.851
SDL15279.1
Magnesium chelatase family protein.
 
 
 0.830
SDK90235.1
Leader peptidase (prepilin peptidase) / N-methyltransferase.
  
  
 0.763
SDK96624.1
Competence protein ComEC.
 
  
 0.761
SDL29441.1
Flagellar motor switch protein FliN/FliY.
  
    0.750
fliP
Flagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.
  
    0.645
codY
Transcriptional pleiotropic repressor; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
       0.583
Your Current Organism:
Clostridium cochlearium
NCBI taxonomy Id: 1494
Other names: ATCC 17787, BCRC 14471, Bacillus cochlearius, C. cochlearium, CCRC 14471, CCRC:14471, CCUG 31665, CIP 104319, Clostridium cochlearum, Clostridium lentoputrescens, NCCB 73036, NCIMB 10633, NCTC 13027
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