STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptsGPTS system, glucose-specific IIABC component; PTS system D-glucosamine-specific IIA component, Glc family /PTS system D-glucosamine-specific IIB component, Glc family /PTS system D-glucosamine-specific IIC component, Glc family. (668 aa)    
Predicted Functional Partners:
SDL16598.1
Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 0.999
ptsH
Phosphocarrier protein.
 
 0.998
sacY
Transcriptional antiterminator, BglG family.
 
 
 0.996
SDL39848.1
Glucokinase.
  
 0.996
nagB
Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
 
 0.990
rpiR
Transcriptional regulator, RpiR family.
  
 
 0.983
gmuF
Mannose-6-phosphate isomerase, type 1.
 
  
 0.980
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
 
  
 0.978
glmS
Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.976
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
   
 
 0.969
Your Current Organism:
Clostridium cochlearium
NCBI taxonomy Id: 1494
Other names: ATCC 17787, BCRC 14471, Bacillus cochlearius, C. cochlearium, CCRC 14471, CCRC:14471, CCUG 31665, CIP 104319, Clostridium cochlearum, Clostridium lentoputrescens, NCCB 73036, NCIMB 10633, NCTC 13027
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