AMH93766.1 protein (methanogenic archaeon ISO4H5)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

AMH93766.1

Hypothetical protein. (101 aa)

Predicted Functional Partners:

AMH93844.1

0.682

AMH94478.1

0.674

AMH95543.1

0.672

AMH95384.1

0.663

AMH95059.1

0.659

AMH94210.1

0.656

AMH95526.1

0.647

rpl39e

0.629

AMH94346.1

0.623

AMH94506.1

0.609

Your Current Organism:

methanogenic archaeon ISO4H5

NCBI taxonomy Id: 1495144
Other names: Thermoplasmatales archaeon enrichment culture clone ISO4-H5, m. archaeon ISO4-H5, methanogenic archaeon ISO4-H5, methanogenic archaeon mixed culture ISO4-H5

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMH93766.1	AMH93844.1	AR505_0041	AR505_0122	Hypothetical protein.	Metal-dependent protease.	0.682
AMH93766.1	AMH94210.1	AR505_0041	AR505_0489	Hypothetical protein.	Amino acid-binding protein with ACT domain protein.	0.656
AMH93766.1	AMH94346.1	AR505_0041	AR505_0625	Hypothetical protein.	Hypothetical protein; Belongs to the UPF0179 family.	0.623
AMH93766.1	AMH94478.1	AR505_0041	AR505_0757	Hypothetical protein.	Phosphoserine phosphatase SerB.	0.674
AMH93766.1	AMH94506.1	AR505_0041	AR505_0785	Hypothetical protein.	Peptidase M50 family (6 TMHs).	0.609
AMH93766.1	AMH95059.1	AR505_0041	AR505_1344	Hypothetical protein.	Amidohydrolase.	0.659
AMH93766.1	AMH95384.1	AR505_0041	AR505_1669	Hypothetical protein.	Hypothetical protein.	0.663
AMH93766.1	AMH95526.1	AR505_0041	AR505_1811	Hypothetical protein.	Transcriptional regulator.	0.647
AMH93766.1	AMH95543.1	AR505_0041	AR505_1828	Hypothetical protein.	Signal peptidase I.	0.672
AMH93766.1	rpl39e	AR505_0041	AR505_0778	Hypothetical protein.	Ribosomal protein L39e Rpl39e; Belongs to the eukaryotic ribosomal protein eL39 family.	0.629
AMH93844.1	AMH93766.1	AR505_0122	AR505_0041	Metal-dependent protease.	Hypothetical protein.	0.682
AMH93844.1	AMH94210.1	AR505_0122	AR505_0489	Metal-dependent protease.	Amino acid-binding protein with ACT domain protein.	0.653
AMH93844.1	AMH94346.1	AR505_0122	AR505_0625	Metal-dependent protease.	Hypothetical protein; Belongs to the UPF0179 family.	0.684
AMH93844.1	AMH94478.1	AR505_0122	AR505_0757	Metal-dependent protease.	Phosphoserine phosphatase SerB.	0.685
AMH93844.1	AMH94506.1	AR505_0122	AR505_0785	Metal-dependent protease.	Peptidase M50 family (6 TMHs).	0.630
AMH93844.1	AMH95384.1	AR505_0122	AR505_1669	Metal-dependent protease.	Hypothetical protein.	0.650
AMH93844.1	AMH95526.1	AR505_0122	AR505_1811	Metal-dependent protease.	Transcriptional regulator.	0.670
AMH93844.1	AMH95543.1	AR505_0122	AR505_1828	Metal-dependent protease.	Signal peptidase I.	0.646
AMH93844.1	rpl39e	AR505_0122	AR505_0778	Metal-dependent protease.	Ribosomal protein L39e Rpl39e; Belongs to the eukaryotic ribosomal protein eL39 family.	0.595
AMH94210.1	AMH93766.1	AR505_0489	AR505_0041	Amino acid-binding protein with ACT domain protein.	Hypothetical protein.	0.656

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

21

average node degree:

3.82

avg. local clustering coefficient:

0.643

expected number of edges:

14

PPI enrichment p-value:

0.0389

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019439

Aromatic compound catabolic process

8 of 56

1.57

2.65

7.00e-09

GO:0009056

Catabolic process

9 of 193

1.09

1.28

9.89e-07

GO:0042537

Benzene-containing compound metabolic process

3 of 10

1.89

1.25

0.0034

GO:0019619

3,4-dihydroxybenzoate catabolic process

2 of 3

2.24

0.82

0.0312

GO:0044282

Small molecule catabolic process

4 of 92

1.06

0.57

0.0371

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0051213

Dioxygenase activity

4 of 13

1.91

1.83

0.00016

GO:0005506

Iron ion binding

4 of 13

1.91

1.83

0.00016

GO:0008199

Ferric iron binding

2 of 3

2.24

0.97

0.0160

GO:0004497

Monooxygenase activity

3 of 20

1.59

0.95

0.0106

GO:0016702

Oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

2 of 5

2.02

0.83

0.0278

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1699

Mixed, incl. Degradation of aromatic compounds, and Coenzyme A transferase

4 of 27

1.59

1.21

0.0022

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map01220

Degradation of aromatic compounds

5 of 30

1.64

2.02

1.07e-05

map00362

Benzoate degradation

5 of 31

1.62

2.0

1.07e-05

map00643

Styrene degradation

2 of 4

2.12

1.17

0.0061

map00361

Chlorocyclohexane and chlorobenzene degradation

2 of 5

2.02

1.13

0.0069

map00622

Xylene degradation

2 of 14

1.57

0.74

0.0321

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0223

Dioxygenase

3 of 8

1.99

1.47

0.0013

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00775

Dioxygenase

2 of 2

2.42

0.8

0.0349

PF00111

2Fe-2S iron-sulfur cluster binding domain

2 of 2

2.42

0.8

0.0349

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