STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
top6BDNA topoisomerase VI subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (682 aa)    
Predicted Functional Partners:
top6A
DNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family.
 
 
 0.985
AMH94111.1
Transmembrane protein.
       0.581
AMH95123.1
RNA-binding protein.
  
     0.558
AMH95231.1
Translation initiation factor aIF-2 alpha subunit.
  
 
 
 0.557
dnaG
DNA primase DnaG; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
   
 0.538
atpF
Archaeal/vacuolar-type H+-ATPase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
     0.526
rpl18e
Ribosomal protein L18e Rpl18e; Belongs to the eukaryotic ribosomal protein eL18 family.
  
     0.519
rpl21e
Ribosomal protein L21e Rpl21e; Belongs to the eukaryotic ribosomal protein eL21 family.
  
     0.502
AMH94112.1
formamidopyrimidine-DNA glycosylase MutM.
       0.483
AMH94113.1
Transmembrane protein.
       0.483
Your Current Organism:
methanogenic archaeon ISO4H5
NCBI taxonomy Id: 1495144
Other names: Thermoplasmatales archaeon enrichment culture clone ISO4-H5, m. archaeon ISO4-H5, methanogenic archaeon ISO4-H5, methanogenic archaeon mixed culture ISO4-H5
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.