STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMH95022.1Hydrogenase expression/formation protein HypD. (359 aa)    
Predicted Functional Partners:
AMH93916.1
Hydrogenase assembly chaperone HypC/HupF.
 
 
 0.999
AMH93802.1
Hydrogenase expression/formation protein HypE.
 
 0.993
hypA
Hydrogenase nickel insertion protein HypA2; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.903
AMH93789.1
Hydrogenase accessory protein HypB.
 
  
 0.896
AMH94196.1
Hydrogenase maturation factor HypF.
 
  
 0.865
AMH95023.1
Hypothetical protein.
       0.775
AMH95191.1
Methyl viologen-reducing hydrogenase alpha subunit MvhA.
 
 
 0.710
AMH95019.1
Bifunctional protein FolC2.
     
 0.565
nth
Endonuclease III Nth; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
       0.561
AMH95018.1
Asparagine synthase (glutamine-hydrolyzing) AsnB2.
       0.497
Your Current Organism:
methanogenic archaeon ISO4H5
NCBI taxonomy Id: 1495144
Other names: Thermoplasmatales archaeon enrichment culture clone ISO4-H5, m. archaeon ISO4-H5, methanogenic archaeon ISO4-H5, methanogenic archaeon mixed culture ISO4-H5
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.