STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMH95458.15'-nucleotidase SurE. (508 aa)    
Predicted Functional Partners:
purA
Adenylosuccinate synthase PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.931
tmk
Thymidylate kinase Tmk2.
  
 
  0.931
AMH95500.1
Ribokinase RbsK.
  
 
 0.926
AMH94463.1
Adenylosuccinate lyase PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 
 0.923
AMH94820.1
Thymidylate kinase Tmk1.
 
 
  0.923
AMH95371.1
Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH.
     
 0.920
apt
Adenine phosphoribosyltransferase Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.913
AMH94023.1
Adenine phosphoribosyltransferase Apt2.
    
 0.913
AMH95211.1
Adenine phosphoribosyltransferase Apt3.
    
 0.913
AMH94192.1
Quinolinate phosphoribosyltransferase nadC.
    
 0.910
Your Current Organism:
methanogenic archaeon ISO4H5
NCBI taxonomy Id: 1495144
Other names: Thermoplasmatales archaeon enrichment culture clone ISO4-H5, m. archaeon ISO4-H5, methanogenic archaeon ISO4-H5, methanogenic archaeon mixed culture ISO4-H5
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