STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMH95483.1Acetolactate synthase small subunit IlvN. (120 aa)    
Predicted Functional Partners:
ilvC
Ketol-acid reductoisomerase IlvC; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
 
 0.989
AMH93874.1
Acetolactate synthase large subunit IlvB1.
  
 0.979
AMH93875.1
Acetolactate synthase large subunit IlvB2.
  
 0.979
AMH94263.1
Thiamine pyrophosphate-requiring protein; Belongs to the TPP enzyme family.
  
 0.979
AMH94355.1
3-isopropylmalate dehydrogenase LeuB.
  
 0.955
AMH95176.1
Alpha-acetolactate decarboxylase BudA.
     
 0.916
AMH94152.1
Pyruvate ferredoxin oxidoreductase alpha subunit PorA.
  
 
 0.912
AMH94352.1
2-isopropylmalate synthase LeuA; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.911
AMH94153.1
Pyruvate ferredoxin oxidoreductase beta subunit.
    
  0.905
AMH94150.1
Pyruvate ferredoxin oxidoreductase gamma subunit PorC.
    
  0.902
Your Current Organism:
methanogenic archaeon ISO4H5
NCBI taxonomy Id: 1495144
Other names: Thermoplasmatales archaeon enrichment culture clone ISO4-H5, m. archaeon ISO4-H5, methanogenic archaeon ISO4-H5, methanogenic archaeon mixed culture ISO4-H5
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