DO97_04915 protein (Neosynechococcus sphagnicola)

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

DO97_04915

Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)

Predicted Functional Partners:

DO97_19800

0.839

DO97_04850

0.801

DO97_16345

0.801

DO97_15700

0.542

DO97_01470

0.422

Your Current Organism:

Neosynechococcus sphagnicola

NCBI taxonomy Id: 1497020
Other names: Chroococcales cyanobacterium sy1, N. sphagnicola sy1, Neosynechococcus sphagnicola sy1

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Browse interactions in tabular form:

Network Stats

number of nodes:

11

number of edges:

26

average node degree:

4.73

avg. local clustering coefficient:

0.941

expected number of edges:

31

PPI enrichment p-value:

0.838

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006284

Base-excision repair

5 of 22

2.45

3.83

3.44e-08

GO:0006281

DNA repair

7 of 250

1.54

2.32

1.46e-07

GO:0006259

DNA metabolic process

8 of 345

1.46

2.24

3.97e-08

GO:0006285

Base-excision repair, AP site formation

2 of 8

2.49

1.27

0.0046

GO:0090305

Nucleic acid phosphodiester bond hydrolysis

4 of 166

1.48

1.21

0.0014

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003906

DNA-(apurinic or apyrimidinic site) endonuclease activity

4 of 6

2.92

3.86

7.63e-08

GO:0140097

Catalytic activity, acting on DNA

6 of 150

1.7

2.44

7.10e-07

GO:0008408

3-5 exonuclease activity

3 of 22

2.23

1.86

0.00028

GO:0016796

Exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5-phosphomonoesters

3 of 25

2.17

1.8

0.00034

GO:0008309

Double-stranded DNA exodeoxyribonuclease activity

2 of 2

3.09

1.73

0.00074

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005634

Nucleus

9 of 2544

0.64

0.45

0.0088

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:9912

Base-excision repair

5 of 12

2.71

4.81

7.49e-10

CL:9917

DNA-(apurinic or apyrimidinic site) endonuclease activity

4 of 6

2.92

4.13

2.42e-08

CL:9547

DNA metabolic process

8 of 198

1.7

3.19

7.49e-10

CL:14867

Purine-containing compound salvage, and Nucleotide catabolism

3 of 29

2.11

1.61

0.00077

CL:9553

Mixed, incl. Mismatch repair, and HDR through Single Strand Annealing (SSA)

3 of 70

1.73

1.07

0.0068

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03410

Base excision repair

5 of 47

2.12

3.47

4.57e-08

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-73621

Pyrimidine catabolism

2 of 3

2.92

1.25

0.0056

MAP-74259

Purine catabolism

2 of 14

2.25

0.9

0.0222

MAP-8956319

Nucleotide catabolism

2 of 16

2.19

0.89

0.0222

MAP-196807

Nicotinate metabolism

2 of 17

2.16

0.89

0.0222

MAP-73894

DNA Repair

4 of 240

1.32

0.8

0.0140

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF03372

Endonuclease/Exonuclease/phosphatase family

2 of 6

2.62

0.96

0.0181

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR041823

YHR202W-like, N-terminal metallophosphatase domain

2 of 2

3.09

1.09

0.0107

IPR036907

5-Nucleotidase, C-terminal domain superfamily

2 of 3

2.92

1.09

0.0107

IPR014485

Predicted phosphoesterase, C1039.02 type

2 of 2

3.09

1.09

0.0107

IPR006179

5-Nucleotidase/apyrase

2 of 3

2.92

1.09

0.0107

IPR004808

AP endonuclease 1

2 of 2

3.09

1.09

0.0107

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00478

Endonuclease III

2 of 5

2.7

1.31

0.0042

Enrichment display settings

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node1	node2	node1 annotation	node2 annotation	score
DO97_01470	DO97_04915	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.422
DO97_01470	DO97_19800	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Polysaccharide export protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.576
DO97_04850	DO97_04915	Polysaccharide/polyol phosphate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.801
DO97_04850	DO97_16345	Polysaccharide/polyol phosphate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.583
DO97_04850	DO97_19800	Polysaccharide/polyol phosphate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Polysaccharide export protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.798
DO97_04915	DO97_01470	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.422
DO97_04915	DO97_04850	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Polysaccharide/polyol phosphate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.801
DO97_04915	DO97_15700	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily.	0.542
DO97_04915	DO97_16345	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.801
DO97_04915	DO97_19800	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Polysaccharide export protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.839
DO97_15700	DO97_04915	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.542
DO97_15700	DO97_19800	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily.	Polysaccharide export protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.469
DO97_16345	DO97_04850	Phosphate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Polysaccharide/polyol phosphate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.583
DO97_16345	DO97_04915	Phosphate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.801
DO97_16345	DO97_19800	Phosphate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Polysaccharide export protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.798
DO97_19800	DO97_01470	Polysaccharide export protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.576
DO97_19800	DO97_04850	Polysaccharide export protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Polysaccharide/polyol phosphate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.798
DO97_19800	DO97_04915	Polysaccharide export protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.839
DO97_19800	DO97_15700	Polysaccharide export protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily.	0.469
DO97_19800	DO97_16345	Polysaccharide export protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.798