node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EP56_04105 | birA | EP56_04105 | EP56_04665 | Hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.541 |
EP56_04105 | panB | EP56_04105 | EP56_04680 | Hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.981 |
EP56_04105 | panC | EP56_04105 | EP56_04685 | Hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.975 |
EP56_05150 | birA | EP56_05150 | EP56_04665 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.757 |
EP56_05150 | cmk | EP56_05150 | EP56_04475 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.633 |
EP56_05150 | coaA | EP56_05150 | EP56_12815 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.892 |
EP56_05150 | coaX | EP56_05150 | EP56_08225 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Hypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.921 |
EP56_05150 | panB | EP56_05150 | EP56_04680 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.459 |
EP56_05150 | panC | EP56_05150 | EP56_04685 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.925 |
EP56_05150 | panD | EP56_05150 | EP56_04690 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Hypothetical protein; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.508 |
EP56_17810 | panC | EP56_17810 | EP56_04685 | Glutamate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the group II decarboxylase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.806 |
EP56_17810 | panD | EP56_17810 | EP56_04690 | Glutamate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the group II decarboxylase family. | Hypothetical protein; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.739 |
EP56_17850 | panC | EP56_17850 | EP56_04685 | Glutamate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the group II decarboxylase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.806 |
EP56_17850 | panD | EP56_17850 | EP56_04690 | Glutamate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the group II decarboxylase family. | Hypothetical protein; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.739 |
birA | EP56_04105 | EP56_04665 | EP56_04105 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.541 |
birA | EP56_05150 | EP56_04665 | EP56_05150 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.757 |
birA | coaA | EP56_04665 | EP56_12815 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Pantothenate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.530 |
birA | coaX | EP56_04665 | EP56_08225 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Hypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.807 |
birA | panB | EP56_04665 | EP56_04680 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.710 |
birA | panC | EP56_04665 | EP56_04685 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.851 |