STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EP56_11775HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)    
Predicted Functional Partners:
EP56_00110
PTS beta-glucoside transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.790
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
  0.779
cinA
Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family.
    
 0.764
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
   
 
  0.742
EP56_03395
Trehalose permease IIC protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.722
EP56_11260
PTS alpha-glucoside transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.722
EP56_15915
Permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.722
EP56_16940
PTS glucose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.721
EP56_11770
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.675
EP56_06255
Acetaldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
    
  0.625
Your Current Organism:
Listeriaceae bacterium FSLA50209
NCBI taxonomy Id: 1497679
Other names: L. bacterium FSL A5-0209, Listeriaceae bacterium FSL A5-0209
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.