U14_01489 protein (Moduliflexus flocculans) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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Score

U14_01489

Protein-tyrosine phosphatase, low molecular weight. (156 aa)

Predicted Functional Partners:

U14_02129

0.939

U14_05967

0.917

U14_03146

0.908

U14_04243

0.908

U14_01878

0.906

U14_04078

0.906

U14_05990

0.906

U14_05961

0.899

ybeY

0.894

U14_00833

0.894

Your Current Organism:

Moduliflexus flocculans

NCBI taxonomy Id: 1499966
Other names: C. Moduliflexus flocculans, Candidatus Moduliflexus flocculans, bacterium UASB14

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
U14_00833	U14_01489	U14_00833	U14_01489	Rhodanese domain protein.	Protein-tyrosine phosphatase, low molecular weight.	0.894
U14_00833	U14_05961	U14_00833	U14_05961	Rhodanese domain protein.	Deoxyribodipyrimidine photolyase.	0.892
U14_00833	U14_05967	U14_00833	U14_05967	Rhodanese domain protein.	Multidomain redox protein, NAD/FAD-dependent oxidoreductase; Rhodanese domain, SirA-like redox domain; Belongs to the sulfur carrier protein TusA family.	0.942
U14_00833	ybeY	U14_00833	U14_00602	Rhodanese domain protein.	Probable rRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.	0.905
U14_01489	U14_00833	U14_01489	U14_00833	Protein-tyrosine phosphatase, low molecular weight.	Rhodanese domain protein.	0.894
U14_01489	U14_01878	U14_01489	U14_01878	Protein-tyrosine phosphatase, low molecular weight.	Thioredoxin.	0.906
U14_01489	U14_02129	U14_01489	U14_02129	Protein-tyrosine phosphatase, low molecular weight.	General stress protein.	0.939
U14_01489	U14_03146	U14_01489	U14_03146	Protein-tyrosine phosphatase, low molecular weight.	Hypothetical protein.	0.908
U14_01489	U14_04078	U14_01489	U14_04078	Protein-tyrosine phosphatase, low molecular weight.	Thioredoxin; Belongs to the thioredoxin family.	0.906
U14_01489	U14_04243	U14_01489	U14_04243	Protein-tyrosine phosphatase, low molecular weight.	Capsular polysaccharide biosynthesis protein.	0.908
U14_01489	U14_05961	U14_01489	U14_05961	Protein-tyrosine phosphatase, low molecular weight.	Deoxyribodipyrimidine photolyase.	0.899
U14_01489	U14_05967	U14_01489	U14_05967	Protein-tyrosine phosphatase, low molecular weight.	Multidomain redox protein, NAD/FAD-dependent oxidoreductase; Rhodanese domain, SirA-like redox domain; Belongs to the sulfur carrier protein TusA family.	0.917
U14_01489	U14_05990	U14_01489	U14_05990	Protein-tyrosine phosphatase, low molecular weight.	Thioredoxin.	0.906
U14_01489	ybeY	U14_01489	U14_00602	Protein-tyrosine phosphatase, low molecular weight.	Probable rRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.	0.894
U14_01878	U14_01489	U14_01878	U14_01489	Thioredoxin.	Protein-tyrosine phosphatase, low molecular weight.	0.906
U14_01878	U14_05967	U14_01878	U14_05967	Thioredoxin.	Multidomain redox protein, NAD/FAD-dependent oxidoreductase; Rhodanese domain, SirA-like redox domain; Belongs to the sulfur carrier protein TusA family.	0.478
U14_02129	U14_01489	U14_02129	U14_01489	General stress protein.	Protein-tyrosine phosphatase, low molecular weight.	0.939
U14_02129	U14_05967	U14_02129	U14_05967	General stress protein.	Multidomain redox protein, NAD/FAD-dependent oxidoreductase; Rhodanese domain, SirA-like redox domain; Belongs to the sulfur carrier protein TusA family.	0.468
U14_03146	U14_01489	U14_03146	U14_01489	Hypothetical protein.	Protein-tyrosine phosphatase, low molecular weight.	0.908
U14_03146	U14_04243	U14_03146	U14_04243	Hypothetical protein.	Capsular polysaccharide biosynthesis protein.	0.801

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Network Stats

number of nodes:

2

number of edges:

1

average node degree:

1

avg. local clustering coefficient:

1

expected number of edges:

1

PPI enrichment p-value:

0.5

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016570

Histone modification

6 of 89

1.91

3.1

6.62e-08

GO:0016573

Histone acetylation

4 of 33

2.16

2.75

2.85e-06

GO:0045893

Positive regulation of transcription, DNA-templated

7 of 165

1.71

2.74

6.62e-08

GO:0051123

RNA polymerase II preinitiation complex assembly

3 of 24

2.17

2.03

0.00011

GO:0016578

Histone deubiquitination

2 of 2

3.08

1.94

0.00031

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003713

Transcription coactivator activity

4 of 20

2.38

2.78

4.57e-06

GO:0003712

Transcription coregulator activity

5 of 81

1.87

2.41

4.57e-06

GO:0046982

Protein heterodimerization activity

3 of 34

2.02

1.41

0.0018

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000124

SAGA complex

10 of 19

2.8

11.63

4.29e-24

GO:0046695

SLIK (SAGA-like) complex

3 of 5

2.86

3.2

1.28e-06

GO:0005669

Transcription factor TFIID complex

3 of 17

2.32

2.41

2.30e-05

GO:0043231

Intracellular membrane-bounded organelle

11 of 4898

0.43

0.36

0.00073

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3955

SAGA complex

8 of 17

2.75

8.53

1.66e-17

CL:3960

SAGA complex

6 of 11

2.81

6.68

1.83e-13

CL:3963

SAGA complex

4 of 6

2.9

4.29

1.15e-08

CL:4304

Transcription factor TFIID complex

3 of 10

2.56

2.48

2.35e-05

CL:4305

Transcription factor TFIID complex

2 of 5

2.68

1.49

0.0019

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03022

Basal transcription factors

3 of 72

1.7

1.14

0.0043

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-5689880

Ub-specific processing proteases

4 of 77

1.79

1.61

0.00040

MAP-5688426

Deubiquitination

4 of 114

1.62

1.37

0.00091

MAP-76042

RNA Polymerase II Transcription Initiation And Promoter Clearance

3 of 51

1.85

1.24

0.0033

MAP-75953

RNA Polymerase II Transcription Initiation

3 of 51

1.85

1.24

0.0033

MAP-73779

RNA Polymerase II Transcription Pre-Initiation And Promoter Opening

3 of 51

1.85

1.24

0.0033

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0070461

SAGA-type complex

6 of 15

2.68

6.08

1.73e-12

GOCC:0000124

SAGA complex

5 of 13

2.66

5.04

2.28e-10

GOCC:0005654

Nucleoplasm

10 of 287

1.62

3.52

3.17e-13

GOCC:1990234

Transferase complex

8 of 397

1.38

2.14

1.04e-08

GOCC:0071819

DUBm complex

2 of 3

2.9

1.9

0.00035

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0396

Initiation factor

3 of 41

1.94

1.44

0.0014

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR009072

Histone-fold

3 of 29

2.09

1.16

0.0064

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