STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
U14_03012Hypothetical protein. (497 aa)    
Predicted Functional Partners:
U14_00941
DNA gyrase subunit B.
   
 
 0.956
U14_04842
ATP-dependent DNA helicase, RecQ family.
  
 
 0.894
U14_01932
alpha-L-arabinofuranosidase.
    
 
 0.889
U14_02436
ATP-dependent DNA helicase recQ.
  
 
 0.889
U14_03364
ATP-dependent DNA helicase domain protein.
  
 
 0.889
U14_00072
Hypothetical protein.
    
 
 0.887
U14_04086
Hypothetical protein.
    
 
 0.887
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 
 0.816
U14_03008
Hypothetical protein.
   
 0.780
U14_01403
YD repeat protein.
  
 
 0.774
Your Current Organism:
Moduliflexus flocculans
NCBI taxonomy Id: 1499966
Other names: C. Moduliflexus flocculans, Candidatus Moduliflexus flocculans, bacterium UASB14
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