STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (558 aa)    
Predicted Functional Partners:
U14_05247
3-isopropylmalate dehydratase large subunit 2.
 
 0.972
U14_05474
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.959
U14_05248
3-isopropylmalate dehydratase, small subunit; Belongs to the LeuD family.
 
 
 0.941
U14_02702
3-isopropylmalate dehydrogenase.
 
 0.938
U14_00742
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 0.932
U14_02458
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 0.932
U14_05472
Acetolactate synthase.
 
 
 0.913
U14_05471
Acetolactate synthase, small subunit.
 
 
 0.912
U14_03817
propionyl-CoA carboxylase carboxyltransferase subunit.
  
 0.910
U14_02333
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 
 0.909
Your Current Organism:
Moduliflexus flocculans
NCBI taxonomy Id: 1499966
Other names: C. Moduliflexus flocculans, Candidatus Moduliflexus flocculans, bacterium UASB14
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