STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpBTryptophan synthase beta chain 2; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (455 aa)    
Predicted Functional Partners:
xseB
Exodeoxyribonuclease 7 small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
  
    0.656
U27_04011
Serine hydroxymethyltransferase.
    
  0.622
U27_06025
Aminomethyltransferase.
    
  0.622
U27_03630
Hypothetical protein.
  
  
  0.611
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
    
 0.607
U27_04019
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
    
 0.607
U27_01345
Homoserine dehydrogenase.
    
  0.606
U27_02793
CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
  
  0.598
U27_05289
Pyridoxal-dependent decarboxylase.
    
  0.569
U27_05934
Glutamate decarboxylase and related PLP-dependent protein.
    
  0.569
Your Current Organism:
Vecturithrix granuli
NCBI taxonomy Id: 1499967
Other names: C. Vecturithrix granuli, Candidatus Vecturithrix granuli, bacterium UASB270
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.