node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SMG15109.1 | SMG29912.1 | SAMN06296010_0590 | SAMN06296010_1647 | Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II. | HAD-superfamily subfamily IB hydrolase, TIGR01490. | 0.712 |
SMG15109.1 | SMG29957.1 | SAMN06296010_0590 | SAMN06296010_1650 | Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II. | 1-acyl-sn-glycerol-3-phosphate acyltransferase. | 0.471 |
SMG15231.1 | SMG29912.1 | SAMN06296010_0608 | SAMN06296010_1647 | Cystathionine beta-synthase. | HAD-superfamily subfamily IB hydrolase, TIGR01490. | 0.764 |
SMG15231.1 | SMG32011.1 | SAMN06296010_0608 | SAMN06296010_1875 | Cystathionine beta-synthase. | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.828 |
SMG15231.1 | glyA | SAMN06296010_0608 | SAMN06296010_1809 | Cystathionine beta-synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.930 |
SMG29906.1 | SMG29912.1 | SAMN06296010_1646 | SAMN06296010_1647 | Hypothetical protein. | HAD-superfamily subfamily IB hydrolase, TIGR01490. | 0.767 |
SMG29906.1 | SMG29919.1 | SAMN06296010_1646 | SAMN06296010_1648 | Hypothetical protein. | Hypothetical protein. | 0.752 |
SMG29906.1 | SMG29926.1 | SAMN06296010_1646 | SAMN06296010_1649 | Hypothetical protein. | Hypothetical protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.537 |
SMG29906.1 | SMG29957.1 | SAMN06296010_1646 | SAMN06296010_1650 | Hypothetical protein. | 1-acyl-sn-glycerol-3-phosphate acyltransferase. | 0.537 |
SMG29906.1 | SMG29969.1 | SAMN06296010_1646 | SAMN06296010_1651 | Hypothetical protein. | Alkyldihydroxyacetonephosphate synthase. | 0.537 |
SMG29912.1 | SMG15109.1 | SAMN06296010_1647 | SAMN06296010_0590 | HAD-superfamily subfamily IB hydrolase, TIGR01490. | Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II. | 0.712 |
SMG29912.1 | SMG15231.1 | SAMN06296010_1647 | SAMN06296010_0608 | HAD-superfamily subfamily IB hydrolase, TIGR01490. | Cystathionine beta-synthase. | 0.764 |
SMG29912.1 | SMG29906.1 | SAMN06296010_1647 | SAMN06296010_1646 | HAD-superfamily subfamily IB hydrolase, TIGR01490. | Hypothetical protein. | 0.767 |
SMG29912.1 | SMG29919.1 | SAMN06296010_1647 | SAMN06296010_1648 | HAD-superfamily subfamily IB hydrolase, TIGR01490. | Hypothetical protein. | 0.773 |
SMG29912.1 | SMG29926.1 | SAMN06296010_1647 | SAMN06296010_1649 | HAD-superfamily subfamily IB hydrolase, TIGR01490. | Hypothetical protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.820 |
SMG29912.1 | SMG29957.1 | SAMN06296010_1647 | SAMN06296010_1650 | HAD-superfamily subfamily IB hydrolase, TIGR01490. | 1-acyl-sn-glycerol-3-phosphate acyltransferase. | 0.917 |
SMG29912.1 | SMG29969.1 | SAMN06296010_1647 | SAMN06296010_1651 | HAD-superfamily subfamily IB hydrolase, TIGR01490. | Alkyldihydroxyacetonephosphate synthase. | 0.914 |
SMG29912.1 | SMG32011.1 | SAMN06296010_1647 | SAMN06296010_1875 | HAD-superfamily subfamily IB hydrolase, TIGR01490. | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.755 |
SMG29912.1 | glyA | SAMN06296010_1647 | SAMN06296010_1809 | HAD-superfamily subfamily IB hydrolase, TIGR01490. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.673 |
SMG29912.1 | hisH | SAMN06296010_1647 | SAMN06296010_3078 | HAD-superfamily subfamily IB hydrolase, TIGR01490. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.670 |