STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (262 aa)    
Predicted Functional Partners:
proA
Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 0.999
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
 0.977
SMG38039.1
Glutamate synthase (NADH) large subunit.
    
 0.949
SMG19073.1
Ornithine--oxo-acid transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
 0.914
obg
GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
  
  
 0.900
SMG46360.1
Acetylornithine aminotransferase apoenzyme.
   
 0.856
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
   
 
 0.840
SMG19352.1
L-proline dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.827
SMG26573.1
L-proline dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.827
glyQS
glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 
    0.791
Your Current Organism:
Agreia pratensis
NCBI taxonomy Id: 150121
Other names: A. pratensis, Agreia pratensis (Behrendt et al. 2002) Schumann et al. 2003, DSM 14246, JCM 12145, LMG 21000, LMG:21000, NBRC 103054, Subtercola pratensis, Subtercola pratensis Behrendt et al. 2002, Subtercola sp. P229/10, VKM Ac-2510, strain P 229/10
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